Uses: Diuretics

Specification: IP/BP/EP/USP

CAS No: 2016-88-8

Chemical Name: 3,5-Diamino-N-carbamimidoyl-6-chloro-2-pyrazinecarboxamide hydrochloride 

Product Specifications:

Appearance:- pale yellow to greenish yellow crystalline powder

Solubility:- Dimethylsulfoxide

Residue on ignition:-NMT 0.1%

Heavy Metals:- NMT 20ppm

Loss on drying:- 11.0/13.0%

Water:-  11.0/13.0%

Free acid:- NMT 0.3ml

Chromatographic purity by TLC:- sum of impurities:-  NMT1%

Assay:- By titration :- 98.0/101.0%

Residual solvents by GLC

·        Acetone:- NMT 500ppm

·        Ethanol:- NMT 500ppm

·        Methanol:-NMT 50ppm

·        Methylene chloride:-NMT 100ppm

·        Chloroform:-NMT 50ppm

Identification:-HPLC

Uses: Cardiovascular

Specification: IP/BP/EP/USP

CAS No: 19774-82-4

Chemical Name: (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone hydrochloride, 2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

Appearance:-White or almost white crystalline powder

Clarity of solution:-The solution is clear and not more intensely coloured than reference solution GY5 or BY5

pH:-3.2~3.8

Related Substance

·        Impurity A :- NMT 0.2%

·        Impurity B:-NMT 0.2%

·        Impurity C:-NMT 0.2%

·        Impurity D :-NMT 0.2%

·        Impurity E:-NMT 0.2%

·        Impurity F:-NMT 0.2%

·        Impurity G:-NMT 0.2%

·        Impurity H:-NMT 0.2%

  Any other impurity:-NMT 0.10%

  Total impurities:-NMT 0.5%

Heavy metals:- NMT 20PPM

Iodides:- NMT 150PPM

Loss on drying: - NMT 0.5%

Sulphated ash:- NMT 0.1%

Assay: 98.0 % to 101.0 %

Identification:- HPLC

Uses: used drugs act on the dopaminergic system in the striatum..  

Specification: IP/BP/EP/USP

CAS No: 14919-77-8 

Product Specifications:

Appearance:- A white or yellowish-white or orange-white crystalline powder

Identification:- IR Chlorides

Optical rotation :- 0.05° to  +0.05°

pH :- 4.0 to 5.0

Related substances:-

·        Impurity A:-        NMT 0.5%   

·        Impurity B:-     NMT 0.5%

·        Impurity C:-     NMT 0.5%

·        Any impurity:-  NMT 0.1%

·        Total impurities:-  NMT 1.0%

Heavy metals:-NMT 20 PPM

Water :- NMT 1.0%

Sulphated ash:- NMT 0.1%

Residual solvents:-

·        Ethanol    :-  NMT 4000 PPM

·        Methanol   :- NMT 2000 PPM

·        Ether     :-NMT 4000 PPM

Assay:- 98.5% to 101.0%

Uses: Diuretic

Specification: IP/BP/EP/USP

CAS No: 976-71-6

ProDesc:

Product Specifications:

Appearance:-Yellow Crystalline Powder                     

 Melting Point:- 150ºc To 165ºc

Related Substances:-

   Single Impurities:- NMT 2.5%

   Total Impurities:- NMT 6.0%

Loss On Drying:- NMT 0.5%

Assay:- NLT 90.0%

CAS No :58-54-8

Uses :Anti-diuretics

Specification  : IP/BP/EP/USP
ProDesc:

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

CAS No :49562-28-9

Uses :Anti-hyperuricaemic agent

Specification  :

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

Assay : NLT 98.0 % and NMT 101.0 %

CAS No :135-09-1

Uses :Heart failure, Hepatic cirrhosis, and Corticosteroid 

Specification  :

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

Assay : NLT 98.0 % and NMT 101.0 %

CAS No :16051-77-7

Uses :Diuretics

Specification  :

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

Assay : NLT 98.0 % and NMT 101.0 %

CAS No :87-33-2

Uses :Used pharmacologically as a vasodilator

Specification  :

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

Assay : NLT 98.0 % and NMT 101.0 %

CAS No :87-33-2

Uses :Used pharmacologically as a Vasodilator

Specification  :
ProDesc:

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

•    Methanol: NMT 0.5 %
  
•    Acetone : NMT 0.5 %
  
•    Ethanol: NMT 0.5 %
  

Assay : NLT 98.0 % and NMT 101.0 %

CAS No :52-01-7

Uses :Used as Diuretic

Specification  <
ProDesc:

Product Specifications

Appearance  : White to off-white powder

Identification : IR, HPLC

Residue on Ignition : NMT 0.2 %

Water content : NMT 0.5%

Heavy metals : NMT 10 PPM

Residual Solvents :

   Methanol: NMT 0.5 %
   Acetone : NMT 0.5 %
   Ethanol: NMT 0.5 %

Related substances :    Single impurity : NMT 0.5%
                                  Total impurities : NMT 1.0%

Assay : NLT 98.0 % and NMT 101.0 %